Why is Rheumatoid Arthritis Becoming Common
Increasing prevalence of rheumatoid arthritis
Rheumatoid Arthritis (RA) is an autoimmune disease that affects approximately 1.3 million Americans and is a chronic inflammatory disorder causing damage to the joints, tendons, and other organs in the body. Once considered a rarer form of arthritis, RA has become increasingly more common over the past few decades, leading to researchers around the world attempting to uncover why the disease is becoming more prevalent.
Factors for the rise of rheumatoid arthritis
There are several key causes for the rising incidence of RA. One major factor is environmental exposure to toxins, such as certain pesticides, hazardous materials, or other industrial chemicals. Certain workplace exposure to these toxins has been linked to an increased risk of developing RA, as these environmental toxins can interfere with the immune system and make individuals more susceptible to developing autoimmune diseases. Other environmental exposures, such as lead or silica, have also been associated with a higher risk of developing RA.
Genetics also play a role in RA prevalence. While there is no single genetic cause for developing the disorder, it is believed that there are multiple genetic factors that may increase a person’s risk, such as the family history of RA, gene mutations, and other genetic variations. Additionally, there are certain immune deficiencies that are associated with a higher risk of developing the condition, such as certain types of T-cell deficiencies, or IgM and IgA deficiencies.
Disorientation of daily lifestyle habits for the development of RA
Lifestyle factors, the duration of certain illnesses, and certain medical treatments, such as long-term use of antibiotics, have all been linked to an increased risk of developing RA. Also, stress has been associated with an increased risk of developing RA, as stress can cause the body to produce inflammatory signals that can interfere with normal immune system functioning.
Lastly, lifestyle factors are found to play an important role in the rise of RA. Poor diet and lack of physical exercise can be contributing factors to the increased risk of developing RA due to the change in the regulation of the immune system which can lead to an increase in inflammation in the joints and in turn, increase the risk of RA. In addition, obesity is a known risk factor of developing RA as it can lead to an increase in inflammation and hormonal imbalances, which in turn increases the risk of RA in an individual.
Other less known effective and problematic factors which are less implied as the major leading cause
Infections have also been linked to the development of RA, as certain bacteria and viruses can trigger an inflammatory response in the body and trigger the development of RA in those with genetically susceptible backgrounds.
Finally, age and gender can also increase an individual’s RA risk. On average, RA diagnosis usually occurs in individuals between the ages of 40-60 and is more common among women.
Environmental causative setup for the rise of RA
In terms of environmental causes, it is found that the rate of the rise of RA increases in the urban areas of the population due to various environmental factors such as exposure to pollution and water contaminants. Pollution is known to release heavy metals and other toxins in the atmosphere that can lead to an increase in inflammation in the joints, which results in an increased risk of developing RA. Additionally, exposure to these toxins can disturb immune regulation and can lead to an increase in RA. Similarly, water contaminants such as an excessive amount of lead can also lead to an increased susceptibility of the bacterium to develop RA.
Genetic predisposition to RA
In terms of genetic factors, it is proved that genetic predisposition can be a key factor in the increased risk of developing RA. Studies have found that individuals who have certain HLA types have an increased risk of developing RA as compared to other individuals. For instance, in individuals with high levels of HLA-DRB1, it is more likely that may develop RA than other individuals. Moreover, certain genes have been linked to increased levels of inflammation, which can in turn increase the risk of RA.
Underlying determinant factors of Rheumatoid Arthritis
RA appears to be becoming increasingly more common in recent years due to a variety of environmental, genetic, lifestyle, and medical factors. It is important to understand these underlying causes of RA in order to develop better treatments for the disorder and help individuals maintain optimal health and reduce their risk.
Treatment by Tofajak
Rheumatoid arthritis can range from mild to severe; Tofajak 5mg Tablet is used to treat it. Fighting inflammation aids in lowering joint discomfort, soreness, and swelling. Additionally, it aids in delaying the deterioration of bones and joints.
Conclusion
Overall, Rheumatoid Arthritis is a chronic autoimmune disorder that can lead to erosive destruction of the joints of the body and can be attributed to many environmental, genetic, and lifestyle factors. Identifying and managing these risks can help to reduce the occurrence of the disorder and, in turn, lead to a lower incidence rate of the disorder in the population.
